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Article

ESBL plasmids in <i>Klebsiella pneumoniae</i>: diversity, transmission, and contribution to infection burden in the hospital setting

2021-12-27

Abstract excerpt

<h4>Background</h4> Resistance to third-generation cephalosporins, often mediated by extended-spectrum beta-lactamases (ESBLs), is a considerable issue in hospital-associated infections as few drugs remain for treatment. ESBL genes are often located on large plasmids that transfer horizontally between strains and species of Enterobacteriaceae and frequently confer resistance to additional drug classes. While plasm...

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Literature Corpus work
d2f4f970-a1f9-5739-a0c6-0d4265730990
DOI
10.1101/2021.12.20.21268000
Open publication

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ESBL plasmids in <i>Klebsiella pneumoniae</i>: diversity, transmission, and contribution to infection burden in the hospital settingDOI 10.1101/2021.12.20.21268000
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