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Genomic surveillance of carbapenem-resistant <i>Klebsiella</i> in Wales reveals persistent spread of <i>K. pneumoniae</i> ST307 and adaptive evolution of pOXA-48-like plasmids

2022-05-25

Abstract excerpt

Rising rates of multi-drug resistant Klebsiella infections necessitate a comprehensive understanding of the major strains and plasmids driving spread of resistance elements. Here we analysed 540 Klebsiella isolates recovered from patients across Wales between 2007 and 2020 using combined short- and long-read sequencing approaches. We identified resistant clones that have spread within and between hospitals inclu...

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Literature Corpus work
54cfaf76-443b-56f2-a5ce-2decbe7214e4
DOI
10.1101/2022.05.25.492139
Open publication

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Genomic surveillance of carbapenem-resistant <i>Klebsiella</i> in Wales reveals persistent spread of <i>K. pneumoniae</i> ST307 and adaptive evolution of pOXA-48-like plasmidsDOI 10.1101/2022.05.25.492139
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