Back to search

Article

Cost-Effectiveness of Combined GnRHa and rhGH Therapy versus Monotherapy in Girls with Central Precocious Puberty Based on a Markov Model Integrating Real-World and Pooled Published Cohort Data

2026-07-25

Abstract excerpt

<title>Abstract</title> <p>Background Gonadotropin-releasing hormone agonist (GnRHa) is the standard treatment for central precocious puberty (CPP), but residual height deficits relative to genetic target height remain common with monotherapy. Adding recombinant human growth hormone (rhGH) improves height outcomes but substantially increases cost and injection burden. Health-economic evidence on this combination...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d23dff0b-b366-51c8-8e7f-a21c55bb2661
DOI
10.21203/rs.3.rs-10155844/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cost-Effectiveness of Combined GnRHa and rhGH Therapy versus Monotherapy in Girls with Central Precocious Puberty Based on a Markov Model Integrating Real-World and Pooled Published Cohort DataDOI 10.21203/rs.3.rs-10155844/v1
The efficacy and safety of pharmacotherapy for girls with central precocious puberty or early puberty: a retrospective cohort studySemantic proximity
Combination therapy of GnRHa, rhGH and Anastrozole to improve final adult height deficit in CAH children with CPPSemantic proximity
Combination therapy of GnRHa, RhGH and anastrozole to improve final adult height deficit in CAH children with CPP.Semantic proximity
Analysis of risk factors affecting the growth potential of girls with precocious puberty and early puberty：a retrospective case-control studySemantic proximity
Adult Height in Girls with Idiopathic Central Precocious PubertySemantic proximity
Safety and Effectiveness of Recombinant Human Growth Hormone in Children with Turner Syndrome: Data from the PATRO Children StudySemantic proximity
Design of the long-term observational cohort study with recombinant human growth hormone in Korean children: LG Growth StudySemantic proximity
Predictors of reproductive and non-reproductive outcomes of gonadotropin mediated pubertal induction in male patients with congenital hypogonadotropic hypogonadism (CHH).Semantic proximity
Comparison of Cumulative Live Birth Rates and Cost-Effectiveness Between GnRH Antagonist and Progestin-Primed Ovarian Stimulation Protocols Running title: Cost-effectiveness of GnRH-ant vs PPOSSemantic proximity
Global and regional trends and age-period-cohort effects in polycystic ovary syndrome burden from 1990 to 2019, with predictions to 2040Semantic proximity
Establishment and application of real-world datasets for precocious puberty from electronic health records based on large language modelsSemantic proximity
The effect of GnRH-analogue therapy on the quality of life of girls with central precocious puberty and their familiesSemantic proximity
Select a neighboring publication to make it the new centre.