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Article

Combination therapy of GnRHa, RhGH and anastrozole to improve final adult height deficit in CAH children with CPP.

BMC pediatrics - 7 May 2025

Liu Xiaoxiao, Liu Fei, Qi Yingyi, Han Xinyi, Ma Shifeng, Zheng Rongxiu

Abstract excerpt

BACKGROUND: To investigate the clinical and genetic characteristics of classic congenital adrenal hyperplasia (CAH) patients. To determine whether gonadotropin-releasing hormone analogs (GnRHa) + recombinant human growth hormone (rhGH) + Anastrozole combined therapy improves the final adult height of CAH patients with central precocious puberty (CPP). METHODS: We described the clinical and genetic characteristics...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40329244
DOI: 10.1186/s12887-025-05703-8
PMCID: PMC12057127

Genes

PAH
CYP21A2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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