Article

Dynamic ventral disc contraction is necessary for <i>Giardia</i> attachment and host pathology

2023-07-04

Abstract excerpt

Giardia lamblia is a common parasitic protist that infects the small intestine and causes giardiasis, resulting in diarrhea, vomiting, weight loss, and malabsorption. Giardiasis leads to cellular damage, including loss of microvilli, disruption of tight junctions, impaired barrier function, enzyme inhibition, malabsorption, and apoptosis. In the host, motile Giardia trophozoites attach to the duodenal microvilli...

Identifiers and source

Literature Corpus work: d237a26e-9eb7-5f4e-b8cb-3d779345fd19
DOI: 10.1101/2023.07.04.547600

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