Article

AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME (ALPS) or AUTOIMMUNE LYMPHOPROLIFERATIVE IMMUNODEFICIENCY (ALPID): THE ONGOING DIAGNOSTIC DILEMA: A CASE SERIES.

2025-10-17

Abstract excerpt

<h4>Background: </h4> Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare inherited disorder of lymphocyte apoptosis characterized by chronic non-malignant lymphadenopathy, splenomegaly, autoimmune cytopenias, and an increased risk of lymphoma. The diagnostic hallmark is expansion of double-negative T cells (DNTs: CD3+ TCRαβ+ CD4– CD8–). Reports from low and middle-income countries remain limited, and diagnos...

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Literature Corpus work: d2207728-b69c-5b36-a992-4144ad59ae15
DOI: 10.22541/au.176068450.09169283/v1

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