Article

Whether CAR-T cell bridging to allo-HSCT increases the incidence of graft-versus-host disease in patients with high-risk chronic lymphocytic leukemia

2020-07-28

Abstract excerpt

<h4>Background: </h4> The TP53 aberration[both del(17p) and TP53 mutations], a high-risk prognostic factor in patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL), is closely related to drug-resistance, rapid disease progression, and short-term survival. Although novel agents, such as ibrutinib, idelalisib, as well as venetoclax, have shown good responses, allogenic hematopoietic stem...

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Literature Corpus work: d1a42034-1afb-5f75-8d35-0718881bc3d4
DOI: 10.21203/rs.3.rs-48474/v1

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