Article

Metatranscriptomic Profiling of Alzheimer’s Brains Suggests a Shift from Putative Commensals to Opportunistic Taxa

2026-03-05

Abstract excerpt

Alzheimer’s disease (AD) is characterized by progressive cognitive decline and the accumulation of amyloid β (Aβ) plaques and tau neurofibrillary tangles. Beyond genetic and proteostatic mechanisms, a growing body of work has revived infection- and dysbiosis-based models of AD, including the antimicrobial protection hypothesis in which Aβ participates in innate immune defense. Here, we reanalyzed ribosomal-deplete...

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Literature Corpus work: d1751ae0-0cd0-5af6-9e82-6d6b8f767d23
DOI: 10.20944/preprints202603.0485.v1

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Metatranscriptomic Profiling of Alzheimer’s Brains Suggests a Shift from Putative Commensals to Opportunistic TaxaDOI 10.20944/preprints202603.0485.v1Read

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