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Gut microbiome alterations in preclinical Alzheimer’s disease

29 Nov 2022

Abstract excerpt

BACKGROUND: Although some human studies have reported gut microbiome changes in individuals with Alzheimer's disease (AD) dementia or mild cognitive impairment (MCI), gut microbiome alterations in preclinical AD, i.e., cerebral amyloidosis without cognitive impairment, is largely unknown. OBJECTIVE: We aimed to identify gut microbial alterations associated with preclinical AD by comparing cognitively normal (CN)...

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PMID: 36445883
DOI: 10.1371/journal.pone.0278276

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