Back to search

Article

Identification of miRNA-mRNA associations in hepatocellular carcinoma using hierarchical integrative model

2020-03-25

Abstract excerpt

<title>Abstract</title> <p>Background: The established role miRNA-mRNA regulation of gene expression has in oncogenesis highlights the importance of integrating miRNA with downstream mRNA targets. These findings call for investigations aimed at identifying disease-associated miRNA-mRNA pairs. Hierarchical integrative models (HIM) offer the opportunity to uncover the relationships between disease and the levels of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d0e30d93-2654-5ce2-ab5e-6591f5007b82
DOI
10.21203/rs.2.16175/v4
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Identification of miRNA-mRNA associations in hepatocellular carcinoma using hierarchical integrative modelDOI 10.21203/rs.2.16175/v4
A novel method for identifying potential disease-related miRNAs via a disease-miRNA-target heterogeneous network.Semantic proximity
Integration of Multiple Genomic and Phenotype Data to Infer Novel miRNA-Disease Associations.Semantic proximity
Comprehensive analysis of negatively correlated miRNA-mRNA regulatory pairs associated with breast cancer diagnosisSemantic proximity
Integrative analysis identifies key mRNA biomarkers for diagnosis, prognosis, and therapeutic targets of HCV-associated hepatocellular carcinomaSemantic proximity
Incorporating higher order network structures to improve miRNA-disease association prediction based on functional modularity.Semantic proximity
An Integrated mRNA-lncRNA Signature for Overall Survival Prediction in CholangiocarcinomaSemantic proximity
Screening prognosis-related lncRNAs based on WGCNA to establish a new risk score for predicting prognosis in patients with hepatocellular carcinomaSemantic proximity
Identification and Evaluation of Metabolic mRNAs and Key miRNAs in Colorectal Cancer Liver MetastasisSemantic proximity
PanomiR: A systems biology framework for analysis of multi-pathway targeting by miRNAsSemantic proximity
Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion.Semantic proximity
Comprehensive analysis of differentially expressed miRNAs in Hepatocellular carcinoma: prognostic significance and pathway insightsSemantic proximity
A novel computational model based on super-disease and miRNA for potential miRNA-disease association prediction.Semantic proximity
Select a neighboring publication to make it the new centre.