Article

DiscoTope-3.0 - Improved B-cell epitope prediction using AlphaFold2 modeling and inverse folding latent representations

2023-02-05

Abstract excerpt

Accurate computational identification of B-cell epitopes is crucial for the development of vaccines, therapies, and diagnostic tools. However, current structure-based prediction methods face limitations due to the dependency on experimentally solved structures. Here, we introduce DiscoTope-3.0, a markedly improved B-cell epitope prediction tool that innovatively employs inverse folding structure representations an...

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Literature Corpus work: d0c7248e-f016-5161-b5b0-9ec9469201f8
DOI: 10.1101/2023.02.05.527174

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