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NetBCE: An Interpretable Deep Neural Network for Accurate Prediction of Linear B-Cell Epitopes

2022-05-24

Abstract excerpt

Identification of B-cell epitopes (BCEs) plays an essential role in the development of peptide vaccines, immuno-diagnostic reagents, and antibody design and production. In this work, we generated a large benchmark dataset comprising 126,779 experimentally-supported, linear epitope-containing regions in 3567 protein clusters from over 1.3 million B cell assays. Analysis of this curated dataset showed large pathogen...

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Literature Corpus work
0f37373b-bc33-5617-8097-7783758741fe
DOI
10.1101/2022.05.23.493092
Open publication

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NetBCE: An Interpretable Deep Neural Network for Accurate Prediction of Linear B-Cell EpitopesDOI 10.1101/2022.05.23.493092
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