Article

Liquid plug propagation in computer-controlled microfluidic airway-on-a-chip with semi-circular microchannels

2023-05-25

Abstract excerpt

This paper introduces a two-inlet, one-outlet lung-on-a-chip device with semi-circular cross-section microchannels and computer-controlled fluidic switching that enables a broader systematic investigation of liquid plug dynamics in a manner relevant to the distal airways. A leak-proof bonding protocol for micro-milled devices facilitates channel bonding and culture of confluent primary small airway epithelial cell...

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Identifiers and source

Literature Corpus work: d071e725-4458-563a-b79b-e333a7870c95
DOI: 10.1101/2023.05.24.542177

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