Article

Integrating extracellular vesicle and circulating cell-free DNA analysis on a single plasma aliquot from breast cancer patients improves the detection of HER2 positivity

2023-03-02

Abstract excerpt

<h4>Background</h4> Multi-analyte liquid biopsies represents an emerging opportunity for non-invasive cancer assessment. We developed ONCE (ONe Aliquot for Circulating Elements), a novel multi-analytes liquid biopsy approach for the isolation of extracellular vesicles (EVs) and cell-free DNA (cfDNA) from a single aliquot of blood. <h4>Methods</h4> We assessed ONCE performance to classify HER2-positive early-stag...

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Literature Corpus work: cfeb0745-0885-570a-9842-d03bd208b519
DOI: 10.1101/2023.03.02.530645

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