Article

Characterization of the continuous transcriptional heterogeneity in Wilms’ tumors using unsupervised machine learning

2022-06-06

Abstract excerpt

<h4>ABSTRACT</h4> Wilms’ tumors are pediatric malignancies that are thought to arise from faulty kidney development. To date, the course of treatment depends on manual histopathological classification which is difficult since the tumors differ between patients in a continuous manner. Here, we used three computational approaches to characterize the continuous heterogeneity of Wilms’ tumors. We first chose a publis...

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Literature Corpus work: cf918eaa-74b3-5430-b31c-234b5aeea2b6
DOI: 10.1101/2022.06.06.494924

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