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Transcriptomic analysis of pathways associated with αv integrin-related non-canonical autophagy in human B cells

2021-08-02

Abstract excerpt

Autophagy proteins have been linked with development of immune-mediated diseases including lupus, but the mechanisms for this are unclear. We have previously shown that non-canonical autophagy induced by αv-integrins regulates B cell activation by viral and self-antigens in mice. Here we investigated the involvement of this pathway in B cells from human tissue. Our data revealed that autophagy is specifically indu...

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Literature Corpus work
cf65470a-fddd-5b35-b9ab-2a2e5e97abe8
DOI
10.1101/2021.08.02.452710
Open publication

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Transcriptomic analysis of pathways associated with αv integrin-related non-canonical autophagy in human B cellsDOI 10.1101/2021.08.02.452710
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