Back to search

Article

Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses

2021-12-09

Abstract excerpt

The SARS-CoV-2 Delta variant is currently responsible for most infections worldwide, including among fully vaccinated individuals. Although these latter infections are associated with milder COVID-19 disease relative to unvaccinated subjects, the specificity and durability of antibody responses elicited by Delta breakthrough cases remain unknown. Here, we demonstrate that breakthrough infections induce serum bindi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cf626e3a-b7d7-513e-92a7-aed24da8015c
DOI
10.1101/2021.12.08.471707
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responsesDOI 10.1101/2021.12.08.471707
Broad and potent neutralizing antibodies are elicited in vaccinated individuals following Delta/BA.1 breakthrough infectionSemantic proximity
SARS-CoV-2 Delta breakthrough infections in vaccinated patientsSemantic proximity
Ad26.COV2.S breakthrough infections induce high titers of neutralizing antibodies against Omicron and other SARS-CoV-2 variants of concernSemantic proximity
Broad and potent neutralizing mAbs are elicited in vaccinated individuals following Delta/BA.1 breakthrough infectionSemantic proximity
Duration of viral shedding and culture positivity with post-vaccination breakthrough delta variant infectionsSemantic proximity
SARS-CoV-2 breakthrough infections induce somatically hypermutated broadly neutralizing antibodies against heterologous variantsSemantic proximity
Profiling serum immunodominance following SARS-CoV-2 primary and breakthrough infection reveals distinct variant-specific epitope usage and immune imprintingSemantic proximity
Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern.Semantic proximity
Biomarkers of protection against controlled human SARS-CoV-2 Delta variant breakthrough infectionSemantic proximity
COVID-19 breakthrough infection after inactivated vaccine induced robust antibody responses and cross-neutralization of SARS-CoV-2 variants, but less immunity against omicronSemantic proximity
SARS-CoV-2 breakthrough infections enhance T cell response magnitude, breadth, and epitope repertoire.Semantic proximity
Antigenic sin of wild-type SARS-CoV-2 vaccine shapes poor cross-neutralization of BA.4/5/2.75 subvariants in BA.2 breakthrough infectionsSemantic proximity
Select a neighboring publication to make it the new centre.