Article

Manipulation of Sonic hedgehog signaling pathway enhance trans differentiation of human dental pulp stem cells into mature oligodendrocytes and neurons

2025-10-16

Abstract excerpt

<title>Abstract</title> <p>Dental pulp stem (DPS) cells, derived from the neural crest, possess multipotent properties and can be obtained through minimally invasive procedures, making them an attractive candidate for neural regeneration strategies. The Sonic Hedgehog (SHH) signaling pathway and downstream expression of GLI protein family is a key regulator of cell fate determination. GLI expression is associated...

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Literature Corpus work: cea98090-4049-593a-bb9f-e6627bfc506e
DOI: 10.21203/rs.3.rs-7663079/v1

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