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Optimal culture conditions for neurosphere formation and neuronal differentiation from human dental pulp stem cells

1 Jan 2021

Abstract excerpt

OBJECTIVES: Human dental pulp stem cells (DPSCs) have been used to regenerate damaged nervous tissues. However, the methods of committing DPSCs into neural stem/progenitor cells (NSPCs) or neurospheres are highly diverse, resulting in many neuronal differentiation outcomes. This study aims to validate an optimal protocol for inducing DPSCs into neurospheres and neurons. METHODOLOGY: After isolation and...

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PMID: 34614124
DOI: 10.1590/1678-7757-2021-0296

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