Back to search

Article

Response surface methods for optimizingSaccharopolyspora spinosa, a novel macrolide producer

1993-02-01

Abstract excerpt

Strain A83543, recently identified asSaccharopolyspora spinosa, was cultured in a variety of media to optimize macrolide titer. Response surface methodology (RSM) was used to improve the fermentation medium and to characterize the microorganism's response to systematic variations in medium composition. Three sequential RSM studies on wild-type A83543 and two high macrolide-producing mutants showed that each strain...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cea8130e-2e4e-5365-9b48-6b7a656ee6db
DOI
10.1007/bf01583684
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 9 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Response surface methods for optimizingSaccharopolyspora spinosa, a novel macrolide producerDOI 10.1007/bf01583684
Optimization of culture medium for lactosucrose ( G-beta-D-galactosylsucrose) Production by Sterigmatomyces elviae mutant using statistical analysis.Semantic proximity
Improvement of 1,3-dihydroxyacetone production from Gluconobacter oxydans by ion beam implantation.Semantic proximity
Medium optimization for phenazine-1-carboxylic acid production by a gacA qscR double mutant of Pseudomonas sp. M18 using response surface methodology.Semantic proximity
Mutant selection of Hahella chejuensis KCTC 2396 and statistical optimization of medium components for prodigiosin yield-up.Semantic proximity
Optimization of biotransformation from phytosterol to androstenedione by a mutant Mycobacterium neoaurum ZJUVN-08.Semantic proximity
An erythromycin process improvement using the diethyl methylmalonate-responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strain.Semantic proximity
Optimization of the Production of Extracellular Polysaccharide from the Shiitake Medicinal Mushroom Lentinus edodes (Agaricomycetes) Using Mutation and a Genetic Algorithm-Coupled Artificial Neural Network (GA-ANN).Semantic proximity
Decreasing the hyphal branching rate of Saccharopolyspora erythraea NRRL 2338 leads to increased resistance to breakage and increased antibiotic production.Semantic proximity
Optimization of production of monacolin K from gamma-irradiated Monascus mutant by use of response surface methodology.Semantic proximity
Select a neighboring publication to make it the new centre.