Article

Exosomal circPOLK promotes metastasis of NSCLC cells via regulating mir-1204/SOX8 axis

2023-10-06

Abstract excerpt

Non-small cell lung cancer (NSCLC) is the most common subtype of lung cancer, and the prognosis of NSCLC patients is still poor particularly for patients with metastatic disease. Thus, extending the knowledge about the mechanism of metastasis is critical for NSCLC treatment. We demonstrated that hsa_circ_0073052 (circPOLK) was overexpressed in blood exosomes from cancer patients than those from healthy people. Fur...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cdcb4606-c202-56ca-9616-d19ba76f62a9
DOI: 10.21203/rs.3.rs-3394848/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exosomal circPOLK promotes metastasis of NSCLC cells via regulating mir-1204/SOX8 axisDOI 10.21203/rs.3.rs-3394848/v1Read

Circular RNA EPB41 Expression Predicts Unfavorable Prognoses in NSCLC by Regulating miR-486-3p/eIF5A Axis-Mediated StemnessSemantic proximity Read

circMET promotes NSCLC cell proliferation, metastasis, and immune evasion by regulating the miR-145-5p/CXCL3 axisSemantic proximity Read

CircTUBGCP3 facilitates the tumorigenesis of lung adenocarcinoma by sponging miR-885-3pSemantic proximity Read

CircRUNX1 Drives Immune Evasion and anti-PD1 Immunotherapy Resistance in Lung Adenocarcinoma by the miR-4739/PCSK9/MHC I AxisSemantic proximity Read

Bioinformatics Analysis Predicts hsa_circ_0026337/miR-197-3p as a Potential Oncogenic ceRNA Network for Non-small Cell Lung CancersSemantic proximity Read

CircRUNX1 drives the malignant phenotypes of lung adenocarcinoma through mediating the miR-5195-3p/HMGB3 network.Semantic proximity Read

A novel plasma circular RNA circFARSA is a potential biomarker for non-small cell lung cancer.Semantic proximity Read

Elevated circASCC3 Suppresses Antitumor Immunity by Sponging miR-432-5p to Upregulate C5a in Non-small-cell Lung CancerSemantic proximity Read

Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 polarizationSemantic proximity Read

Circular RNA Hsa_Circ_0002483 Promotes Growth and Invasion of Lung Adenocarcinoma by Sponging miR-125a-3pSemantic proximity Read

Understanding the Dual Roles of CircHIPK3 in Tumorigenesis and Tumor ProgressionSemantic proximity Read

Lung CSC-derived exosomal miR-210-3p contributes to a pro-metastatic phenotype in lung cancer by targeting FGFRL1.Semantic proximity Read