Article
CircRUNX1 drives the malignant phenotypes of lung adenocarcinoma through mediating the miR-5195-3p/HMGB3 network.
General thoracic and cardiovascular surgery - 1 Mar 2024
Wang Yan, Li Hui, Chen Wenbin, Huang Xiaoliang, Fan Renliang, Xu Meijia, Zou Li
Abstract excerpt
BACKGROUND: Circular RNAs (circRNAs) are key factors in the regulation of cancer progression. However, the role of circRUNX1 in lung adenocarcinoma (LUAD) progression is unclear. METHODS: The expression levels of circRUNX1, microRNA (miR)-5195-3p, and high-mobility group protein B3 (HMGB3) were detected by quantitative real-time PCR. Cell proliferation, migration, invasion and apoptosis were analyzed by EdU...
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