Article

The discovery of an evolutionarily conserved enhancer within the MYEOV locus suggests an unexpected role for this non-coding region in cancer

2023-09-19

Abstract excerpt

The myeloma overexpressed gene ( MYEOV ) has been proposed to be a proto-oncogene due to high RNA transcript levels found in multiple cancers, including myeloma, breast, lung, pancreas and esophageal cancer. The presence of an open reading frame (ORF) in humans and other primates suggests protein-coding potential. Yet, we still lack evidence of a functional MYEOV protein. It remains undetermined how MYEOV overe...

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Literature Corpus work: cdb3b762-7834-5fbf-b081-aaca7ad962a7
DOI: 10.1101/2023.09.18.558245

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