Article

Whole-exome sequencing of Iranian families identifies novel variants underlying congenital hearing loss

2026-05-28

Abstract excerpt

<title>Abstract</title> <p>Background: Congenital nonsyndromic hearing loss (NSHL) is a highly genetically heterogeneous disorder involving more than 150 genes and numerous rare variants identified worldwide. In consanguineous populations such as Iran, recessive alleles are enriched, making genomic approaches particularly critical. Whole-exome sequencing (WES) has emerged as a powerful diagnostic tool, especially...

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Literature Corpus work: ccb86e1f-49fb-517a-95b6-36c7845bdcbf
DOI: 10.21203/rs.3.rs-8513800/v1

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