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Article

Identification of novel variants in Iranian consanguineous pedigrees with nonsyndromic hearing loss by next-generation sequencing.

Journal of clinical laboratory analysis - 1 Dec 2020

Bitarafan Fatemeh, Seyedena Seyed Yousef, Mahmoudi Mahdi, Garshasbi Masoud

Abstract excerpt

BACKGROUND: The extremely high genetic heterogeneity of hearing loss due to diverse group of genes encoding proteins required for development, function, and maintenance of the complex auditory system makes the genetic diagnosis of this disease challenging. Up to now, 121 different genes have been identified for nonsyndromic hearing loss (NSHL), of which 76 genes are responsible for the most common forms of NSHL,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32864763
DOI: 10.1002/jcla.23544
PMCID: PMC7755797

Genes

CDH23
GIPC3
GJB2
MYO7A
OTOF
TECTA
TRIOBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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