Article

Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition

2024-03-16

Abstract excerpt

<h4>Background</h4> Cardiac dysfunction in AL amyloidosis is thought to be partly related to the direct impact of AL LCs on cardiomyocyte function, with the degree of dysfunction at diagnosis as a major determinant of clinical outcomes. Nonetheless, mechanisms underlying LC-induced myocardial toxicity are not well understood. <h4>Methods</h4> We identified gene expression changes correlating with human cardiac c...

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Literature Corpus work: cc6032d5-9d88-5bfc-a53a-4b6084b065d6
DOI: 10.1101/2024.03.14.584987

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