Article

Left ventricular strain does not differentiate amyloidogenic profiles in at-risk individuals with<i>TTR</i>Val142Ile

2021-01-29

Abstract excerpt

<h4>Objectives</h4> To identify echocardiographic signatures featuring left ventricular longitudinal strain (LS) associated with genetic risk for cardiac amyloidosis (CA) due to the TTR Val142Ile (V142I) variant in African American (AA) and Hispanic/Latinx (H/L) individuals. <h4>Background</h4> Hereditary transthyretin amyloidosis (hATTR) can cause CA in ∼60-70% of older V142I carriers, but amyloid deposition prog...

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Literature Corpus work: a2275416-6c5b-51a3-97b5-700a264f70a1
DOI: 10.1101/2021.01.26.21250565

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