Article

Expression of thrombin-cleaved osteopontin and integrin α9 and β1 signaling pathway molecules in chronic subdural hematomas

2022-10-05

Abstract excerpt

<title>Abstract</title>Chronic subdural hematoma (CSDH) is considered to be an inflammatory and angiogenic disease. The CSDH outer membrane, which contains inflammatory cells, plays an important role in CSDH development. Osteopontin (OPN) is an extracellular matrix protein that is cleaved by thrombin, generating the N-terminal half of OPN, which is prominently involved in integrin signal transduction. We explor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cbf23b7a-c45b-54f2-b04b-2915c3a2df3a
DOI: 10.21203/rs.3.rs-1181122/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Expression of thrombin-cleaved osteopontin and integrin α9 and β1 signaling pathway molecules in chronic subdural hematomasDOI 10.21203/rs.3.rs-1181122/v2Read

Neovascularization in the outer membrane of chronic subdural hematomas from the dural border cell layer of the dura materSemantic proximity Read

Proteomic Profiling of Extracellular Vesicles Derived from Human Serum for the Discovery of Biomarkers in Avascular NecrosisSemantic proximity Read

Thrombin Cleavage of Osteopontin Modulates Its Activities in Human CellsIn Vitroand Mouse Experimental Autoimmune EncephalomyelitisIn VivoSemantic proximity Read

Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recoverySemantic proximity Read

Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases.Semantic proximity Read

OPN gene polymorphism and the serum OPN levels confer the susceptibility and prognosis of ischemic stroke in Chinese patients.Semantic proximity Read

Involvement of neutrophils in machineries underlying the rupture of intracranial aneurysmsSemantic proximity Read

Significance of Coagulation and Fibrinolysis Markers for Benign and Malignant Soft Tissue TumorsSemantic proximity Read

Efficacy and safety analysis of a new hemostatic gelatin matrix for spinal surgery: A randomized controlled studySemantic proximity Read

Down‐regulation of exosomal microRNA‐224‐3p derived from bone marrow–derived mesenchymal stem cells potentiates angiogenesis in traumatic osteonecrosis of the femoral headSemantic proximity Read

A Novel Cryptic Binding Motif, LRSKSRSFQVSDEQY, in the C-Terminal Fragment of MMP-3/7-Cleaved Osteopontin as a Novel Ligand for α9β1 Integrin Is Involved in the Anti-Type II Collagen Antibody-Induced ArthritisSemantic proximity Read

The relationship between postoperative hypoeosinophilia and hospital stay in patients undergoing hip fracture surgery under general anesthesia or spinal anesthesia: A retrospective studySemantic proximity Read