DVSP: An integrated database of virus spike proteins

Abstract excerpt

Spike protein is a class I virus fusion glycoprotein that plays an important role in cell infection by mediating receptor binding and membrane fusion during virus invasion. The fusion mechanism between virus and host cell mediated by spike protein is complex, and alterations via mutation can affect viral pathogenicity and have been linked with virus pandemics. In-depth studies of the biology and toxicology of viru...

Topics

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• Angiotensin-Converting Enzyme 2
• Betacoronavirus
• Chiroptera
• Protein Conformation, alpha-Helical
• Protein Conformation, beta-Strand
• SARS-CoV-2 and COVID-19 Research
• Severe acute respiratory syndrome-related coronavirus
• Structural Homology, Protein

Identifiers and source

Literature Corpus work

cbbb444d-8f50-5345-889a-bf0fe5d6284f

DOI

10.21203/rs.3.rs-1797991/v1