Embryonic cerebral cortex cells retain CNS phenotypes after transplantation into peripheral nerve.

doi:10.1016/j.expneurol.2004.06.013

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Article

Embryonic cerebral cortex cells retain CNS phenotypes after transplantation into peripheral nerve.

Experimental neurology - 1 Oct 2004

Baez Juan Carlos, Gajavelli Shyam, Thomas Christine K, Grumbles Robert M, Aparicio Beatriz, Byer David, Tsoulfas Pantelis

Abstract excerpt

Differentiation of stem cells depends on environmental cues. In this study, acutely dissociated or expanded cells derived from embryonic day 14 (E14) rat cerebral cortex were transplanted into the distal tibial nerve stump of adult Fischer rats to determine whether a peripheral nervous system (PNS) environment would influence cell differentiation. Acutely dissociated cells, which included neural precursors and...

Topics

Animals
Astrocytes
Brain Tissue Transplantation
Cell Differentiation
Cells, Cultured
Cerebral Cortex
Female
Fetus
Fibroblast Growth Factor 2
Glial Fibrillary Acidic Protein
Glutamate Decarboxylase
Graft Survival
Muscle, Skeletal

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nerve Regeneration

Nerve Tissue Proteins

Neurons

Peripheral Nerves

Phenotype

Source

Open in PubMed

Identifiers

PMID: 15380492
DOI: 10.1016/j.expneurol.2004.06.013

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GFAP

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