Article

A Biophysical Model of Human Colonic Motor Pattern Generation in Health and Disease

2026-04-20

Abstract excerpt

<h4>Purpose</h4> Colonic motility disorders, including diarrhea-predominant irritable bowel syndrome and slow-transit constipation, impose a major clinical burden. Although high-resolution colonic manometry reveals characteristic spatiotemporal motor patterns, such as high-amplitude propagating contractions and cyclic motor pattern in healthy individuals, these patterns are often altered or absent in disease. Und...

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Literature Corpus work: cb56a8d5-a596-5f8e-9ad9-e97016f74500
DOI: 10.64898/2026.04.15.718795

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