Article

Cellular Heterogeneity of Pluripotent Stem Cell Derived Cardiomyocyte Grafts is Mechanistically Linked to Treatable Arrhythmias

2022-09-16

Abstract excerpt

<h4>Background</h4> Exciting pre-clinical data have confirmed that human pluripotent stem cell derived cardiomyocytes (PSC-CMs) can remuscularise the injured or diseased heart, with several clinical trials now in planning or recruitment stages worldwide. However, ventricular arrhythmias are a predictable complication following engraftment of intramyocardially injected PSC-CMs. Therefore, there is an urgent unmet...

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Literature Corpus work: 8b9b67ec-8eab-5109-96d1-b23caa8e4670
DOI: 10.1101/2022.09.15.500719

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