Apoptosis-Related Non-Coding RNAs in Cardiac Fibrosis and Heart Failure: Implications for Pathogenesis and Therapy

Abstract excerpt

Heart failure (HF) and cardiac fibrosis constitute a substantial portion of the global cardiovascular disease (CVD) burden and are significant contributors to morbidity and mortality. Several mechanisms are involved in the pathogenesis of HF and cardiac fibrosis, with many studies recognizing apoptosis as a central player in their progression. Apoptosis is a conserved biological process directly regulated by...

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