Article
β-lactam Antibiotics Stimulate the Pathogenicity of Methicillin-resistant <i>Staphylococcus aureus</i> Via SarA-controlled Tandem Lipoprotein Expression
2018-06-21
Abstract excerpt
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of nosocomial infections worldwide. MRSA resists nearly all β-lactam antibiotics that have a bactericidal activity and a signal inducer effect. However, studies have yet to clarify whether the inducer effect of empirically used β-lactams stimulates MRSA pathogenicity in vivo. Here, we showed that a new cluster of tandem lipoprotein genes ( tlp...
Topics
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- Antimicrobial Peptides and Activities
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Biochemical and Structural Characterization
- Infective Endocarditis Diagnosis and Management
- Plant-Microbe Interactions and Immunity
- Streptococcal Infections and Treatments
Identifiers and source
- Literature Corpus work
- cade86ca-df59-5c1d-964e-afc9d3a7a68a
- DOI
- 10.1101/353227
