CPT1B-Mediated Fatty Acid Oxidation Induces Pigmentation in Solar Lentigo

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Cellular senescence is associated with altered lipid metabolism, including increased cellular lipid uptake, upregulated lipid biosynthesis, and deregulated lipid breakdown. Previous studies have reported that carnitine palmitoyltransferase (CPT), the rate-limiting enzyme in fatty acid oxidation that catalyzes the conversion of acyl-CoA to acylcarnitine, is involved in vari...

Topics

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• Acne and Rosacea Treatments and Effects
• Apolipoprotein A-I
• Apolipoproteins E
• Biochemical Analysis and Sensing Techniques
• Exome Sequencing
• Genetic Heterogeneity
• Lipid Metabolism
• melanin and skin pigmentation

Identifiers and source

Literature Corpus work

cad00c82-fac3-54d4-bb87-242b0c893224

DOI

10.1101/2025.06.15.659823