Article

Multi-tissue proteomics identifies molecular signatures for sporadic and genetically defined Alzheimer disease cases

2021-10-21

Abstract excerpt

<title>Abstract</title> <p>Alzheimer disease (AD) is a heterogeneous disease with many genes are associated with AD risk. Most proteomic studies, while instrumental in identifying AD pathways and genes, focus on single tissues and sporadic AD cases. Multi-tissue proteomic signatures for sporadic and genetically defined AD (e.g., pathogenic variant carriers in APP and PSEN1/2 and risk variant carriers in TREM2) wi...

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Literature Corpus work: c97ec6e9-cebb-54f6-9974-c66ce5a9298f
DOI: 10.21203/rs.3.rs-923492/v1

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