Article

Senescence-associated loss of intestinal α1,2-fucose disrupts a modifiable host-microbiome homeostasis axis in people with HIV

2026-07-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> People with HIV (PWH), despite effective antiretroviral therapy (ART), experience disrupted intestinal homeostasis characterized by microbial dysbiosis and impaired intestinal barrier integrity, which contribute to chronic inflammation and aging-associated comorbidities. However, tractable mechanisms contributing to this dysfunction remain poorly defined. <h4>Objective</h4>...

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Literature Corpus work: c89b3066-67be-59d8-b44b-85f0fea162e0
DOI: 10.64898/2026.07.09.736798

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