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Fecal microbiota transplantation alters the proteomic landscape of inflammation in HIV: identifying bacterial drivers

22 Oct 2024

Abstract excerpt

BACKGROUND: Despite effective antiretroviral therapy, people with HIV (PWH) experience persistent systemic inflammation and increased morbidity and mortality. Modulating the gut microbiome through fecal microbiota transplantation (FMT) represents a novel therapeutic strategy. We aimed to evaluate proteomic changes in inflammatory pathways following repeated, low-dose FMT versus placebo. METHODS: This...

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PMID: 39438902
DOI: 10.1186/s40168-024-01919-5

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