Article

Organochlorine pesticides and epigenetic alterations in brain cancer

2024-11-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Epigenetic alterations have emerged as critical factors in the pathogenesis of brain cancer, particularly gliomas. This article explores the impact of organochlorine pesticides (OCPs) on the hypermethylation of key tumor suppressor genes, and some histone modifications in primary brain tumor (PBT) patients. <bold>Methods:</bold> This study involved 73 patients d...

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Literature Corpus work: c889c2e9-3114-5481-8a8c-2abd45f04a7c
DOI: 10.21203/rs.3.rs-5346737/v1

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