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Epigenetic modulation of RRP22 and P16 genes, and histones H4 and H3 in brain cancer following organochlorine pesticides exposure

2022-07-29

Abstract excerpt

<h4>Background: </h4> Organochlorine pesticide (OCP) exposure and epigenetic modifications have been well-documented in brain cancer incidence; however, their associations remain ambiguous. In this paper, we examined the effect of seven OCPs on the methylation status of two tumor suppressor genes ( RRP22 and P16 ) and four histone marks (H4K16ac, H3K9ac, H4K20me3, and H3k4me2) in 73 patients with a primary brain t...

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Literature Corpus work
8dc8dfd5-44a4-5676-aacd-65d8df5e76aa
DOI
10.21203/rs.3.rs-1887743/v1
Open publication

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