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Article

Pcdh19 Loss-of-Function Increases Neuronal Migration In Vitro but is Dispensable for Brain Development in Mice.

Scientific reports - 31 May 2016

Pederick Daniel T, Homan Claire C, Jaehne Emily J, Piltz Sandra G, Haines Bryan P, Baune Bernhard T, Jolly Lachlan A, Hughes James N, Gecz Jozef, Thomas Paul Q

Abstract excerpt

Protocadherin 19 (Pcdh19) is an X-linked gene belonging to the protocadherin superfamily, whose members are predominantly expressed in the central nervous system and have been implicated in cell-cell adhesion, axon guidance and dendrite self-avoidance. Heterozygous loss-of-function mutations in humans result in the childhood epilepsy disorder PCDH19 Girls Clustering Epilepsy (PCDH19 GCE) indicating that PCDH19 is...

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Identifiers

PMID: 27240640
DOI: 10.1038/srep26765
PMCID: PMC4886214

Genes

PCDH19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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