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Comparative phenotypic, genomic and transcriptomic characterisation of two <i>Salmonella</i> Typhimurium strains for a first-in-human challenge model

2025-04-28

Abstract excerpt

<h4>Background</h4> Invasive non-typhoidal Salmonella (iNTS) disease remains a major public health challenge in sub-Saharan Africa. Salmonella Typhimurium is responsible for the majority of cases, with specific lineages being associated with increased risk of bloodstream infection. We have recently developed a Salmonella Typhimurium controlled human infection model (CHIM) to better understand disease pathogene...

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Literature Corpus work
c7d20f12-207c-5476-8358-e73413c20ae3
DOI
10.1101/2025.04.24.650425
Open publication

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Comparative phenotypic, genomic and transcriptomic characterisation of two <i>Salmonella</i> Typhimurium strains for a first-in-human challenge modelDOI 10.1101/2025.04.24.650425
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