Article

Lack of genetic evidence for a role of SLC25A46 in alpha-synucleinopathies

2026-02-01

Abstract excerpt

<h4>Background</h4> The SLC25A46 gene encodes a mitochondrial carrier protein previously implicated in neuropathy and optic atrophy. Biallelic variants in SLC25A46 have been described in patients with Parkinson’s disease (PD) with optic atrophy, but the evidence supporting a role in PD remains limited. <h4>Objective</h4> To assess whether SLC25A46 variants contribute to PD, REM sleep behavior disorder (RBD),...

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Literature Corpus work: c7d0a653-28ef-5c5d-b5b6-1a43f31b1bbd
DOI: 10.64898/2026.01.30.26344974

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