Genomic epidemiology uncovers the timing and origin of the emergence of mpox in humans

Abstract excerpt

Five years before the 2022–2023 global mpox outbreak Nigeria reported its first cases in nearly 40 years, with the ongoing epidemic since driven by sustained human-to-human transmission. However, limited genomic data has left questions about the timing and origin of the mpox virus’ (MPXV) emergence. Here we generated 112 MPXV genomes from Nigeria from 2021-2023. We identify the closest zoonotic outgroup to the hum...

Topics

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• Disease Outbreaks
• Epidemics
• Genome, Viral
• Genomics
• Molecular Epidemiology
• Mutation
• Phylogeny
• Poxvirus research and outbreaks

Identifiers and source

Literature Corpus work

c7bc9e24-298e-5e69-b978-27c4f46a8e5f

DOI

10.1101/2024.06.18.24309104