Back to search

Article

Genomic epidemiology uncovers the origin of the mpox epidemic in Sierra Leone

2025-10-17

Abstract excerpt

In January 2025, Sierra Leone reported its first mpox case in eight years, followed by a rapid nationwide surge that made it the epicenter of the continental mpox virus (MPXV) Clade IIb A.2.2 outbreak, with more than 5,000 confirmed cases reported by August. To investigate the origin, timing, and spread of this epidemic, we generated 338 high-quality MPXV genomes from cases across 14 districts and conducted Bayesi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d1b43a86-7068-595b-b9e6-7a679bd55942
DOI
10.1101/2025.10.15.25337823
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genomic epidemiology uncovers the origin of the mpox epidemic in Sierra LeoneDOI 10.1101/2025.10.15.25337823
Genomic epidemiology of the 2025 mpox epidemic in Sierra Leone.Semantic proximity
Genomic epidemiology uncovers the timing and origin of the emergence of mpox in humansSemantic proximity
Preliminary report on the molecular epidemiology of mpox, South Africa 2024Semantic proximity
Emergence of mpox in Guinea: sporadic clade IIa cases and a clade IIb upsurgeSemantic proximity
Mpox, Caused by the MPXV of the Clade IIb Lineage, Goes GlobalSemantic proximity
Phylogenetic Analysis of the Mpox Virus in the Sub-Saharan Africa (2022–2024)Semantic proximity
The Evolutionary Dynamics and Regional Spread of Mpox in Africa: Insights from Multi-country Genomic SurveillanceSemantic proximity
Genomic sequence analysis of the first mpox virus detected in KenyaSemantic proximity
Molecular epidemiology of recurrent zoonotic transmission of mpox virus in West AfricaSemantic proximity
Clade IIb mpox outbreak in Sierra LeoneSemantic proximity
First cases of mpox Clade I outside of Africa: genetic insights on its evolutionSemantic proximity
Genomics reveals zoonotic and sustained human mpox spread in West AfricaSemantic proximity
Select a neighboring publication to make it the new centre.