Article
APOBEC3 deaminase editing in mpox virus as evidence for sustained human transmission since at least 2016.
Science (New York, N.Y.) - 3 Nov 2023
O'Toole Áine, Neher Richard A, Ndodo Nnaemeka, Borges Vitor, Gannon Ben, Gomes João Paulo, Groves Natalie, King David J, Maloney Daniel, Lemey Philippe, Lewandowski Kuiama, Loman Nicholas, Myers Richard, Omah Ifeanyi F, Suchard Marc A, Worobey Michael, Chand Meera, Ihekweazu Chikwe, Ulaeto David, Adetifa Ifedayo, Rambaut Andrew
Abstract excerpt
Historically, mpox has been characterized as an endemic zoonotic disease that transmits through contact with the reservoir rodent host in West and Central Africa. However, in May 2022, human cases of mpox were detected spreading internationally beyond countries with known endemic reservoirs. When the first cases from 2022 were sequenced, they shared 42 nucleotide differences from the closest mpox virus (MPXV)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.