Article

Transcriptional profiling to identify therapeutic targets influencing skeletal muscle atrophy

2012-01-01

Abstract excerpt

Skeletal muscle atrophy is characterised by a loss of muscle weight and volume involving a reduction in muscle fibre diameter in the absence of degenerative changes and/or a reduction in the actual number of fibres. In humans there are a wide range of stimuli for skeletal muscle atrophy including bed rest, extreme training, malnutrition and cancer. The underlying cellular and molecular mechanisms governing the pro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c79a848e-e12e-5ee4-a23a-eef569520740
DOI: 10.17638/00009913

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptional profiling to identify therapeutic targets influencing skeletal muscle atrophyDOI 10.17638/00009913Read

Transcriptional response of the neuromuscular system to exercise training and potential implications for ALSSemantic proximity Read

Transcriptomic Signatures and Upstream Regulation in Human Skeletal Muscle Adapted to Disuse and Aerobic Exercise.Semantic proximity Read

Adaptation of the transcriptional response to resistance exercise over 4 weeks of daily training.Semantic proximity Read

Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophySemantic proximity Read

Inhibiting 5-lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signaling and insulin-like growth factor-1Semantic proximity Read

The effect of neuromuscular electrical stimulation on the human skeletal muscle transcriptomeSemantic proximity Read

Expression profiling of skeletal muscle following acute and chronic β2-adrenergic stimulation: implications for hypertrophy, metabolism and circadian rhythmSemantic proximity Read

PGC-1 coactivators and skeletal muscle adaptations in health and diseaseSemantic proximity Read

Transcriptomic analysis of 40 human and rodent skeletal muscle exerkinesSemantic proximity Read

Signalling pathways that mediate skeletal muscle hypertrophy and atrophySemantic proximity Read

Improvement of Duchenne muscular dystrophy phenotype following obestatin treatment.Semantic proximity Read

Comparative molecular analysis of endurance exercise in vivo with electrically stimulated in vitro myotube contractionSemantic proximity Read