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Identification of ADP-ribosylation factor 6 as the cellular target of withangulatin A against TNBC cells by ferroptosis

2022-10-14

Abstract excerpt

<h4>Purpose: </h4> Effective anticancer therapy can be achieved by regulating ADP-ribosylation factor 6 (ARF6) activation, but its biological roles are still challenging and few effective compounds against ARF6 have been identified. WA exerts the anti-proliferative effects on MDA-MB-231 cells. However, its molecular targets and unexplored mechanisms remain elusive. In the present study, our objective was to develo...

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Literature Corpus work
c77ff42e-6747-58a2-971b-4bb6c412c3f6
DOI
10.21203/rs.3.rs-2149466/v1
Open publication

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