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Identification of potential biomarkers for CAD using integration with expression and methylation data and validation by case-control study

2020-02-12

Abstract excerpt

<h4>Background: </h4> DNA methylation plays an essential role in the pathogenesis of coronary artery disease (CAD) through regulating mRNA expressions. This study aimed to identify hub genes as biomarkers functioning in CAD and regulated by DNA methylation. <h4>Methods:</h4> Gene expression and methylation datasets of peripheral blood leukocytes (PBLs) of CAD were downloaded from Gene Expression Omnibus (GEO) data...

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Literature Corpus work
c6d5036e-ae16-59b4-ac8b-641bd4dd03ab
DOI
10.21203/rs.2.23331/v1
Open publication

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Identification of potential biomarkers for CAD using integration with expression and methylation data and validation by case-control studyDOI 10.21203/rs.2.23331/v1
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