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Identification of Potential Biomarkers for CAD Using Integrated Expression and Methylation Data

9 Sept 2020

Abstract excerpt

DNA methylation plays an essential role in the pathogenesis of coronary artery disease (CAD) through regulating mRNA expressions. This study aimed to identify hub genes regulated by DNA methylation as biomarkers of CAD. Gene expression and methylation datasets of peripheral blood leukocytes (PBLs) of CAD were downloaded from the Gene Expression Omnibus (GEO) database. Subsequently, multiple computational...

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PMID: 33033488
DOI: 10.3389/fgene.2020.00778

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